If you’re interested in participating in one of our research studies, please fill out the form at the bottom of the page and someone will be in contact with you.
Asthma Institute Research Registry (AIR)
Asthma — which affects more than 25 million people in the United States — is a chronic lung disease that that causes swelling and inflammation in the airways, making it hard to breathe. Researchers want to better understand asthma by enrolling people with asthma into the Asthma Institute Research Registry. A research registry is a list of individuals who agree to allow researchers to review and study their medical records and allow researchers to contact them about future research study opportunities. Many advancements in medicine have resulted from research involving the collection and analysis of the medical record information of patients with a certain disease or condition.
Exposome of Asthma Patients
Asthma is a chronic disease driven by both your genes and your environment. Researchers would like to better understand how personal exposures to air pollution and other airborne irritants can affect asthma. This is a pilot study of the use of a silicone wristband (the same as ones used to support causes, such as types of cancers) to measure personal exposures to indoor and outdoor air pollution. It is open to participants currently enrolled in the Asthma Institute Research Registry (AIR).
Immune Mechanisms in Severe Asthma (IMSA-2)
Severe asthma, which affects approximately 5%-10% of asthmatics, is poorly understood and difficult to treat. Researchers think that people with severe asthma may have differences in their lungs and blood, when compared to people with milder forms of asthma or no asthma. The purpose of this research study is to look at these differences and find out how they are related to your symptoms and asthma flares over one year. This study is looking for all types of people with asthma along with healthy people.
MCC Study
A study designed to assess mucociliary clearance after 12 weeks of treatment with dupilumab
Many people with asthma have problems with too much mucus (phlegm), and some people may not even know they have too much phlegm because it is stuck in their airways. Too much phlegm can be a sign of more severe/difficult to control asthma and is associated with worse breathing tests. This research study will do two things. First, it will try to help understand why some people with asthma are not able to clear mucus/phlegm from their lungs, as well as where it may stick in the lungs. Second, eligible patients will then be treated with an injectable drug which blocks some types of asthma inflammation or a matching placebo (“sugar water” injection) for 12 weeks to see if blocking this type of asthma inflammation decreases the amount of mucus in the lungs and improves its removal.
Precision Interventions for Severe Asthmatics (PrecISE)
PrecISE is a clinical study that uses precision medicine for severe asthma. Precision medicine is an approach to the prevention and treatment of disease that uses information about an individual’s or group’s specific disease process, symptoms, and treatment responses, to identify the medicines and therapies that are most likely to be effective for them.