New possible link between inflammatory pathways in asthma may help explain severity
We sought to better understand how the underlying immune system is involved in asthma and how interactions between different components of the immune system may affect clinical features of asthma. We focused on a protein, CCL5, which is commonly involved in Type 1 inflammation (a form of inflammation involved in fighting bacteria/viruses and in autoimmune disease). Type 1 inflammation is often very resistant to steroid therapy. We observed that CCL5 was associated with both Type 1…